Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.48 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.48 |
| ▸ | RGS12 | O14924 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733849 | 0.92 | LMNA (0.60) | POLBLMNAMAPK10NPC1RAB9A | |
| SCHEMBL4737760 | 0.88 | GRIK1 (0.57) | LMNANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4734498 | 0.87 | LMNA (0.78) | POLBLMNAMAPK10NPC1RAB9A | |
| SCHEMBL4737597 | 0.84 | POLB (0.59) | POLBLMNAMAPK10NPC1RAB9A | |
| SCHEMBL4735004 | 0.82 | NPC1 (0.54) | POLBLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4738643 | 0.78 | ALDH1A1 (0.59) | POLBLMNAMAPK10NPC1RAB9A | |
| SCHEMBL4749629 | 0.78 | NPC1 (0.61) | POLBLMNAMAPK10NPC1RAB9A | |
| SCHEMBL4749274 | 0.77 | SMN1; SMN2 (0.56) | LMNAMAPK10NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4736542 | 0.76 | SMN1; SMN2 (0.58) | POLBLMNAMAPK10NPC1RAB9A | |
| SCHEMBL4733317 | 0.76 | ALDH1A1 (0.52) | POLBLMNAMAPK10NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008069611-A1 | N-PHENYLAMIDE DERIVATIVE, PROCESS FOR THE PREPARATION THEREOF, AND COMPOSITION FOR PREVENTING OR TREATING ISCHEMIC DISEASES COMPRISING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-06-12 | — | — | WO | claimed |
| US-9364468-B2 | Pharmaceutical composition for preventing or treating tuberculosis | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2016-06-14 | — | — | US | disclosed |
| US-9364468-B2 | Pharmaceutical composition for preventing or treating tuberculosis | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2016-06-14 | — | — | US | disclosed |
| US-20150133503-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING TUBERCULOSIS | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2015-05-14 | — | — | US | disclosed |
| US-20150133503-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING TUBERCULOSIS | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2015-05-14 | — | — | US | disclosed |
| WO-2008069611-A1 | N-PHENYLAMIDE DERIVATIVE, PROCESS FOR THE PREPARATION THEREOF, AND COMPOSITION FOR PREVENTING OR TREATING ISCHEMIC DISEASES COMPRISING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133503-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING TUBERCULOSIS | GCDH, DHODH, MDH1 | POLB 1770/4885LMNA 3805/4885MAPK10 4027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.