Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4732735 | 0.99 | HDAC6 (0.39) | HDAC6RAB9AHDAC1HDAC2MAPT | |
| SCHEMBL4781266 | 0.99 | HDAC6 (0.39) | HDAC6RAB9AHDAC1HDAC2MAPT | |
| SCHEMBL4733721 | 0.99 | HDAC6 (0.39) | HDAC6RAB9AHDAC1HDAC2MAPT | |
| SCHEMBL4732261 | 0.98 | HDAC6 (0.38) | HDAC6RAB9AHDAC1HDAC2MAPT | |
| SCHEMBL5597230 | 0.91 | RAB9A (0.40) | RAB9AMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL20306814 | 0.83 | RAB9A (0.37) | RAB9AMAPTGAAPKMALDH1A1 | |
| SCHEMBL29278219 | 0.79 | ALDH1A1 (0.52) | RAB9AMAPTALDH1A1LMNAESR1 | |
| SCHEMBL8468092 | 0.79 | ALDH1A1 (0.52) | RAB9AMAPTALDH1A1LMNAESR1 | |
| SCHEMBL29278218 | 0.79 | ESR1 (0.51) | RAB9AMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL4767440 | 0.77 | HDAC1 (0.38) | HDAC6RAB9AHDAC1HDAC2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008060931-A2 | METHOD FOR PREPARING FLUORINATED BENZOTRIAZOLE COMPOUNDS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-05-22 | — | — | WO | disclosed |
| US-20080114177-A1 | METHOD FOR PREPARING FLUORINATED BENZOTRIAZOLE COMPOUNDS | 3M INNOVATIVE PROPERTIES COMPANY | 2008-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080114177-A1 | METHOD FOR PREPARING FLUORINATED BENZOTRIAZOLE COMPOUNDS | CYP2E1, FLI1, GABBR1 | HDAC6 1352/4885RAB9A 4283/4885HDAC1 696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.