Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 14/20 | 0.43 |
| ▸ | CNR1 | P21554 | 5/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14206941 | 0.88 | CNR2 (0.42) | CNR2CNR1RIPK1L3MBTL1NPC1 | |
| SCHEMBL14207102 | 0.86 | CNR2 (0.44) | CNR2CNR1RIPK1L3MBTL1NPC1 | |
| SCHEMBL4733265 | 0.85 | CNR2 (0.46) | CNR2CNR1RIPK1L3MBTL1NPC1 | |
| SCHEMBL4731872 | 0.83 | CNR2 (0.45) | CNR2CNR1RIPK1L3MBTL1NPC1 | |
| SCHEMBL4732510 | 0.80 | CNR2 (0.68) | CNR2CNR1 | |
| SCHEMBL4783898 | 0.78 | CNR2 (0.46) | CNR2CNR1L3MBTL1NPC1RAB9A | |
| SCHEMBL4731510 | 0.77 | CNR2 (0.55) | CNR2CNR1RIPK1L3MBTL1NPC1 | |
| SCHEMBL14207101 | 0.76 | CNR2 (0.45) | CNR2CNR1L3MBTL1NPC1RAB9A | |
| SCHEMBL4731808 | 0.75 | RAB9A (0.51) | CNR2RIPK1NPC1RAB9ALMNA | |
| SCHEMBL14207374 | 0.75 | USP2 (0.42) | CNR2CNR1RIPK1L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |