Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 15/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 8/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4730468 | 0.81 | CNR2 (0.43) | CNR2LMNAPOLBCNR1L3MBTL1 | |
| SCHEMBL4733265 | 0.78 | CNR2 (0.46) | CNR2LMNAPOLBCNR1L3MBTL1 | |
| SCHEMBL14206939 | 0.78 | CNR2 (0.46) | CNR2LMNAPOLBCNR1L3MBTL1 | |
| SCHEMBL4733945 | 0.78 | CNR2 (0.43) | CNR2LMNAPOLBCNR1L3MBTL1 | |
| SCHEMBL14207113 | 0.78 | CNR2 (0.41) | CNR2LMNAPOLBCNR1NPC1 | |
| SCHEMBL14207102 | 0.77 | CNR2 (0.44) | CNR2LMNAPOLBCNR1L3MBTL1 | |
| SCHEMBL4735161 | 0.77 | RAB9A (0.46) | CNR2LMNAPOLBCNR1L3MBTL1 | |
| SCHEMBL4734015 | 0.76 | CNR2 (0.57) | CNR2LMNACNR1NPC1RAB9A | |
| SCHEMBL4732528 | 0.75 | CNR2 (0.39) | CNR2LMNAPOLBCNR1L3MBTL1 | |
| SCHEMBL4732956 | 0.75 | LMNA (0.40) | CNR2LMNAPOLBCNR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |