Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 4/20 | 0.37 |
| ▸ | NPY1R | P25929 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733973 | 0.85 | KMT2A (0.45) | NPY5RNPY1RDRD2ADRA2CKMT2A | |
| SCHEMBL25176203 | 0.85 | NPY5R (0.41) | NPY5RNPY1RDRD2ADRA2CKMT2A | |
| SCHEMBL30313896 | 0.85 | NPY5R (0.41) | NPY5RNPY1RDRD2ADRA2CKMT2A | |
| SCHEMBL29903263 | 0.83 | NSD2 (0.45) | NPY5RNPY1RDRD2ADRA2CKMT2A | |
| SCHEMBL29482112 | 0.82 | NPY5R (0.38) | NPY5RNPY1RDRD2ADRA2CKMT2A | |
| SCHEMBL25176450 | 0.80 | KMT2A (0.38) | NPY5RNPY1RDRD2ADRA2CKMT2A | |
| SCHEMBL25434751 | 0.77 | METAP2 (0.39) | NPY5RNPY1RDRD2ADRA2CKMT2A | |
| SCHEMBL21542144 | 0.77 | MAPT (0.55) | KMT2AMEN1ALDH1A1LMNAHTT | |
| SCHEMBL30802159 | 0.77 | MAPT (0.55) | KMT2AMEN1ALDH1A1LMNAHTT | |
| SCHEMBL25170409 | 0.76 | NPY5R (0.37) | NPY5RNPY1RDRD2ADRA2CKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3565815-B1 | COMPOUNDS AS BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS | FOCHON PHARMACEUTICALS LTD (CN) | 2024-03-13 | — | — | EP | disclosed |