Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4738274 | 0.89 | MAPT (0.45) | MAPTTDP1LMNAALDH1A1NPSR1 | |
| SCHEMBL4736772 | 0.85 | MAPT (0.47) | MAPTTDP1LMNAALDH1A1NPSR1 | |
| SCHEMBL4803910 | 0.81 | ALDH1A1 (0.46) | MAPTTDP1ALDH1A1GAAPKM | |
| SCHEMBL3856537 | 0.81 | ALDH1A1 (0.46) | MAPTTDP1LMNAALDH1A1NPSR1 | |
| SCHEMBL4735942 | 0.79 | HTT (0.52) | MAPTTDP1LMNAALDH1A1NPSR1 | |
| SCHEMBL4749651 | 0.79 | KDM4E (0.54) | MAPTTDP1LMNAALDH1A1NPSR1 | |
| SCHEMBL4187378 | 0.78 | KDM4E (0.51) | MAPTTDP1LMNAALDH1A1NPSR1 | |
| SCHEMBL4187568 | 0.76 | ALDH1A1 (0.47) | MAPTTDP1LMNAALDH1A1NPSR1 | |
| SCHEMBL4751445 | 0.74 | L3MBTL1 (0.58) | MAPTTDP1LMNAALDH1A1NPSR1 | |
| SCHEMBL4734500 | 0.74 | L3MBTL1 (0.50) | MAPTALDH1A1SMN1; SMN2L3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008069611-A1 | N-PHENYLAMIDE DERIVATIVE, PROCESS FOR THE PREPARATION THEREOF, AND COMPOSITION FOR PREVENTING OR TREATING ISCHEMIC DISEASES COMPRISING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-06-12 | — | — | WO | claimed |
| WO-2008069611-A1 | N-PHENYLAMIDE DERIVATIVE, PROCESS FOR THE PREPARATION THEREOF, AND COMPOSITION FOR PREVENTING OR TREATING ISCHEMIC DISEASES COMPRISING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-06-12 | — | — | WO | disclosed |