Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4734992 | 0.87 | MMP2 (0.31) | MMP2MMP9 | |
| SCHEMBL4738183 | 0.82 | MMP2 (0.33) | MMP2LMNAMMP9 | |
| SCHEMBL4736141 | 0.79 | CNR1 (0.50) | KDM4E | |
| SCHEMBL4733748 | 0.78 | — | — | |
| SCHEMBL4736890 | 0.78 | — | — | |
| SCHEMBL5140602 | 0.77 | CNR1 (0.32) | — | |
| SCHEMBL4737143 | 0.76 | TDP1 (0.38) | MMP2LMNAMAPTHTTMMP9 | |
| SCHEMBL4524137 | 0.75 | CNR1 (0.40) | KDM4ELMNAALDH1A1GAA | |
| SCHEMBL4736755 | 0.74 | CNR1 (0.56) | KDM4E | |
| SCHEMBL4735344 | 0.74 | ADORA2B (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008076046-A1 | NOVEL 2-AMINO-5, 5-DIARYL-IMIDAZOL-4-ONES | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | disclosed |