Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SFRP1 | Q8N474 | 19/20 | 0.57 |
| ▸ | WNT3 | P56703 | 2/20 | 0.47 |
| ▸ | ADAMTS7 | Q9UKP4 | 1/20 | 0.46 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4785270 | 0.92 | SFRP1 (0.60) | SFRP1WNT3 | |
| SCHEMBL4733669 | 0.88 | SFRP1 (0.56) | SFRP1WNT3ADAMTS7ADAMTS5 | |
| SCHEMBL4734248 | 0.87 | SFRP1 (0.54) | SFRP1WNT3 | |
| SCHEMBL4734816 | 0.87 | SFRP1 (0.59) | SFRP1WNT3 | |
| SCHEMBL4735611 | 0.87 | SFRP1 (0.45) | SFRP1WNT3 | |
| SCHEMBL4734322 | 0.85 | SFRP1 (0.55) | SFRP1WNT3 | |
| SCHEMBL4735911 | 0.85 | SFRP1 (0.54) | SFRP1WNT3 | |
| SCHEMBL4735525 | 0.85 | SFRP1 (0.61) | SFRP1WNT3 | |
| SCHEMBL4781291 | 0.84 | SFRP1 (0.52) | SFRP1WNT3ADAMTS7ADAMTS5 | |
| SCHEMBL4736342 | 0.84 | SFRP1 (0.57) | SFRP1WNT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061016-A1 | N-SUBSTITUTED PIPERIDINYL 4 -ARYLSULFONAMIDES AS MODULATORS OF THE SECRETED FRIZZLED RELATED PROTEIN- 1 | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |