Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA3 | P07451 | 2/20 | 0.31 |
| ▸ | CA5A | P35218 | 2/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20045683 | 0.81 | ALDH1A1 (0.43) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL29241483 | 0.79 | ALDH1A1 (0.41) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL16640879 | 0.79 | — | — | |
| SCHEMBL20050529 | 0.78 | ALDH1A1 (0.50) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL29241535 | 0.76 | ALDH1A1 (0.48) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL16640898 | 0.76 | ALDH1A1 (0.33) | ALDH1A1POLBSMN1; SMN2CA2CA1 | |
| SCHEMBL20051724 | 0.76 | ALDH1A1 (0.54) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL29241624 | 0.74 | SMN1; SMN2 (0.52) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL19170051 | 0.73 | EGLN1 (0.37) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8424916 | 0.71 | ALDH1A1 (0.43) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582696-B1 | 5-ARYL ISOXAZOLINES FOR CONTROLLING PESTS | NOVARTIS AG (CH) | 2014-10-22 | — | — | EP | disclosed |
| WO-2011157748-A1 | 5-ARYL ISOXAZOLINES FOR CONTROLLING PESTS | NOVARTIS AG (CH) | 2011-12-22 | — | — | WO | disclosed |