SCHEMBL16640898

SCHEMBL16640898

NCNC(=O)C(F)(F)C(F)(F)C(F)(F)CF

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
POLB P06746 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL47344 0.76 ALDH1A1 (0.36) ALDH1A1CA1CA2POLBSMN1; SMN2
SCHEMBL92115 0.71
SCHEMBL16640879 0.71
SCHEMBL865707 0.67 THRB (0.32)
SCHEMBL1950932 0.66
SCHEMBL15413473 0.65
SCHEMBL28087298 0.65 ALDH1A1 (0.45) ALDH1A1CA1CA2POLBSMN1; SMN2
SCHEMBL16640889 0.64 ALDH1A1 (0.36) ALDH1A1POLB
SCHEMBL30451082 0.64 THRB (0.34)
SCHEMBL30450888 0.64 THRB (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150105843-A1 METAL COMPLEXES COMPRISING CONDENSED HETEROAROMATIC RINGS UDC IRELAND LIMITED (IE) 2015-04-16 US disclosed