Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 11/20 | 0.54 |
| ▸ | CNR1 | P21554 | 3/20 | 0.51 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4731505 | 0.86 | CNR2 (0.59) | CNR2CNR1BRD4LMNAPOLB | |
| SCHEMBL14206334 | 0.85 | CNR2 (0.52) | CNR2CNR1BRD4ARLMNA | |
| SCHEMBL14206662 | 0.85 | CNR2 (0.56) | CNR2CNR1RIPK1BRD4MAP3K5 | |
| SCHEMBL4731510 | 0.85 | CNR2 (0.55) | CNR2CNR1RIPK1BRD4MAP3K5 | |
| SCHEMBL14206637 | 0.84 | CNR2 (0.54) | CNR2CNR1RIPK1BRD4MAP3K5 | |
| SCHEMBL4733925 | 0.81 | CNR2 (0.51) | CNR2CNR1RIPK1BRD4MAP3K5 | |
| SCHEMBL4731889 | 0.79 | CNR2 (0.56) | CNR2CNR1RIPK1BRD4LMNA | |
| SCHEMBL4731207 | 0.77 | CNR2 (0.64) | CNR2CNR1BRD4 | |
| SCHEMBL4729964 | 0.76 | CNR2 (0.82) | CNR2CNR1 | |
| SCHEMBL4734972 | 0.76 | CNR2 (0.62) | CNR2CNR1RIPK1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |