Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 6/20 | 0.47 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984629 | 0.93 | EPHX1 (0.47) | EPHX1ACHEHRH3NPC1RAB9A | |
| SCHEMBL11072059 | 0.89 | EPHX1 (0.47) | EPHX1ACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6987835 | 0.85 | EPHX1 (0.43) | EPHX1ACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29078672 | 0.85 | EPHX1 (0.43) | EPHX1ACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20835057 | 0.84 | EPHX1 (0.55) | EPHX1ACHEZDHHC7HRH3HRH4 | |
| SCHEMBL5622460 | 0.84 | EPHX1 (0.48) | EPHX1ACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10817069 | 0.82 | EPHX1 (0.52) | EPHX1ACHEZDHHC7HRH3HRH4 | |
| SCHEMBL5496557 | 0.82 | EPHX1 (0.41) | EPHX1ACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29222977 | 0.81 | EPHX1 (0.51) | EPHX1ACHEZDHHC7HRH3HRH4 | |
| SCHEMBL18396951 | 0.81 | EPHX1 (0.50) | EPHX1ACHEZDHHC7HRH3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008059014-A2 | ANTITUBERCULOSIS AGENTS WITH ALKYLIDENE OR ALKYL SIDE CHAIN | UNIVERSIDAD DE SALAMANCA (ES) | 2008-05-22 | — | — | WO | disclosed |