Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6387680 | 0.87 | LMNA (0.49) | EPHX1ACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11072059 | 0.85 | EPHX1 (0.47) | EPHX1ACHEALDH1A1NPC1RAB9A | |
| SCHEMBL6984629 | 0.85 | EPHX1 (0.47) | EPHX1ACHEALDH1A1NPC1RAB9A | |
| SCHEMBL6987835 | 0.84 | EPHX1 (0.43) | EPHX1ACHEALDH1A1NPC1RAB9A | |
| SCHEMBL2344663 | 0.84 | EPHX1 (0.43) | EPHX1ACHEALDH1A1NPC1RAB9A | |
| SCHEMBL6168367 | 0.83 | KMT2A (0.43) | EPHX1ACHEL3MBTL1 | |
| SCHEMBL4778612 | 0.83 | EPHX1 (0.40) | EPHX1ACHEALDH1A1NPC1RAB9A | |
| SCHEMBL5198190 | 0.83 | ZDHHC7 (0.41) | EPHX1ACHEALDH1A1NPC1RAB9A | |
| SCHEMBL4734717 | 0.82 | EPHX1 (0.53) | EPHX1ACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17175563 | 0.82 | EPHX1 (0.39) | EPHX1ACHEALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740547-A1 | PGD2 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005100321-A1 | PGD2 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2005-10-27 | — | — | WO | disclosed |