Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4734717 | 0.93 | EPHX1 (0.53) | EPHX1ACHEHRH3HRH4NPC1 | |
| SCHEMBL11072059 | 0.93 | EPHX1 (0.47) | EPHX1ACHEALDH1A1CTSKNPC1 | |
| SCHEMBL29078672 | 0.88 | EPHX1 (0.43) | EPHX1ACHEALDH1A1CTSKNPC1 | |
| SCHEMBL6987835 | 0.88 | EPHX1 (0.43) | EPHX1ACHEALDH1A1CTSKCA1 | |
| SCHEMBL5622460 | 0.87 | EPHX1 (0.48) | EPHX1ACHEALDH1A1NPC1HPGD | |
| SCHEMBL5496557 | 0.85 | EPHX1 (0.41) | EPHX1ACHEALDH1A1CTSKNPC1 | |
| SCHEMBL14471704 | 0.83 | CTSK (0.49) | EPHX1ACHEALDH1A1CTSKHRH3 | |
| SCHEMBL30483896 | 0.82 | EPHX1 (0.44) | EPHX1ACHEALDH1A1CTSKNPC1 | |
| SCHEMBL1840802 | 0.82 | EPHX1 (0.44) | EPHX1ACHEALDH1A1NPC1HPGD | |
| SCHEMBL6387680 | 0.81 | LMNA (0.49) | EPHX1ACHEHRH3HRH4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289980-A1 | BICYCLYL OR HETEROBICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED N-HYDROXYFORMAMIDES | SMITHKLINE BEECHAM PLC (GB) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001090100-A1 | BICYCLYL OR HETEROBICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED N-HYDROXYFORMAMIDES | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-11-29 | — | — | WO | disclosed |