Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 8/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.70 |
| ▸ | PGR | P06401 | 6/20 | 0.70 |
| ▸ | LMNA | P02545 | 6/20 | 0.70 |
| ▸ | AR | P10275 | 4/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7080634 | 0.92 | NR3C1 (0.62) | NR3C1CYP3A4HIF1APGRLMNA | |
| SCHEMBL4734156 | 0.90 | NR3C1 (0.72) | NR3C1CYP3A4HIF1APGRLMNA | |
| SCHEMBL8204332 | 0.89 | NR3C1 (0.59) | NR3C1CYP3A4HIF1APGRLMNA | |
| SCHEMBL7905893 | 0.89 | NR3C1 (0.58) | NR3C1CYP3A4HIF1APGRLMNA | |
| SCHEMBL11682502 | 0.88 | NR3C1 (0.58) | NR3C1CYP3A4HIF1APGRLMNA | |
| SCHEMBL11682563 | 0.88 | NR3C1 (0.59) | NR3C1CYP3A4HIF1APGRLMNA | |
| SCHEMBL6324239 | 0.87 | NR3C1 (0.56) | NR3C1CYP3A4HIF1APGRLMNA | |
| SCHEMBL11682590 | 0.87 | NR3C1 (0.58) | NR3C1CYP3A4HIF1APGRLMNA | |
| SCHEMBL6323559 | 0.86 | NR3C1 (0.57) | NR3C1CYP3A4HIF1APGRLMNA | |
| SCHEMBL11680004 | 0.86 | NR3C1 (0.58) | NR3C1CYP3A4HIF1APGRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1143950-B1 | TOPICAL APPLICATION PRODUCTS AGAINST ONYCHOMYCOSES | BIOEQUAL AG (CH) | 2005-03-09 | — | — | EP | claimed |
| EP-1680076-B1 | PHARMACEUTICAL AND COSMETIC FORMULATIONS FOR TREATING FINGERNAILS | BIOEQUAL AG (CH) | 2008-07-02 | — | — | EP | disclosed |
| WO-2008049401-A2 | NAIL VARNISH FOR COSMETIC AND MEDICAL APPLICATIONS | SUSILO RUDY (DE) | 2008-05-02 | — | — | WO | disclosed |
| US-20070166249-A1 | Pharmaceutical and cosmetic formulations for treating fingernails | BIOEQUAL AG (CH) | 2007-07-19 | — | — | US | disclosed |
| EP-1680076-A1 | PHARMACEUTICAL AND COSMETIC FORMULATIONS FOR TREATING FINGERNAILS | BioEqual AG (CH) | 2006-07-19 | — | — | EP | disclosed |
| EP-1143950-B1 | TOPICAL APPLICATION PRODUCTS AGAINST ONYCHOMYCOSES | BIOEQUAL AG (CH) | 2005-03-09 | — | — | EP | disclosed |
| WO-2005018585-A1 | PHARMACEUTICAL AND COSMETIC FORMULATIONS FOR TREATING FINGERNAILS | BIOEQUAL AG (CH) | 2005-03-03 | — | — | WO | disclosed |
| US-6740326-B1 | WATER-FREE TOPICAL APPLICATION COMPOSITION FOR TREATMENT OF NAIL DISEASES AND NAIL CARE CONSISTING OF ANTIMYCOTIC AGENT AND LOWER ALKYL ESTER OF LACTIC ACID, MALIC ACID, TARTARIC ACID OR CITRIC ACID AS PENETRATION PROMOTING CARRIER | BIOEQUAL AG (CH) | 2004-05-25 | — | — | US | disclosed |
| EP-0876393-B1 | 21-(2-OXO-TETRAHYDROFURAN)-THIO PREGNANE DERIVATIVES, A PROCESS FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLAXO GROUP LTD (GB) | 2000-07-05 | — | — | EP | disclosed |
| US-6013244-A | AS ANTI-INFLAMMATORY OR ANTI-ALLERGIC AGENTS | GLAXO WELLCOME INC. (US) | 2000-01-11 | — | — | US | disclosed |
| EP-0956047-A1 | NEW CARRIER SYSTEMS | IPR-Institute for Pharmaceutical Research Riehen AG (CH) | 1999-11-17 | — | — | EP | disclosed |
| EP-0570454-B1 | NOVEL STEROIDS | ASTRA AB (SE) | 1999-04-07 | — | — | EP | disclosed |
| EP-0876393-A1 | 21-(2-OXO-TETRAHYDROFURAN)-THIO PREGNANE DERIVATIVES, A PROCESS FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLAXO GROUP LIMITED (GB) | 1998-11-11 | — | — | EP | disclosed |
| WO-1998016251-A1 | NEW CARRIER SYSTEMS | IPR-INSTITUTE FOR PHARMACEUTICAL RESEARCH AG (CH) | 1998-04-23 | — | — | WO | disclosed |
| EP-0572451-B1 | NOVEL STEROID ESTERS | ASTRA AB (SE) | 1998-04-01 | — | — | EP | disclosed |
| WO-1997024367-A1 | 21-(2-OXO-TETRAHYDROFURAN)-THIO PREGNANE DERIVATIVES, A PROCESS FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLAXO GROUP LIMITED (GB) | 1997-07-10 | — | — | WO | disclosed |
| US-5614514-A | Steroid esters | AKTIEBOLAGET ASTRA (SE) | 1997-03-25 | — | — | US | disclosed |