SCHEMBL4734754

SCHEMBL4734754

CCCC(C#N)(CCC)C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 3/20 0.34
ALDH1A1 P00352 2/20 0.34
TSHR P16473 1/20 0.34
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
FFAR3 O14843 1/20 0.31
HDAC3 O15379 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
CYP1A2 P05177 1/20 0.30
THRB P10828 1/20 0.30
CTSS P25774 1/20 0.30
CTSK P43235 1/20 0.30
FDPS P14324 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL31084442 1.00 MCL1 (0.34) MCL1ALDH1A1TSHRMEN1KMT2A
SCHEMBL28015047 0.98 MCL1 (0.33) MCL1ALDH1A1TSHRMEN1KMT2A
SCHEMBL3542104 0.91 ALDH1A1 (0.32) MCL1ALDH1A1TSHRMEN1KMT2A
SCHEMBL7703895 0.86 AKR1B1 (0.34) ALDH1A1TSHRMEN1KMT2ACTSS
SCHEMBL17499002 0.86
Carbonotrithioic Acid SCHEMBL17499005 0.82
SCHEMBL1961638 0.81 CES2 (0.40) ALDH1A1TSHRMEN1KMT2A
SCHEMBL1341696 0.80 ALDH1A1 (0.37) MCL1ALDH1A1TSHRMEN1KMT2A
SCHEMBL27989962 0.80 ALDH1A1 (0.31) ALDH1A1CTSSCTSK
SCHEMBL1341188 0.79 MCL1 (0.37) MCL1ALDH1A1TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119930467-A Preparation method of 2-cyano-2-propyl valerate and valproic acid 湖南省湘中制药有限公司 2025-05-06 CN claimed
CN-118373735-B Valproic acid prepared by cyanoacetic acid ester method 湖南省湘中制药有限公司 2025-02-21 CN claimed
CN-118373735-A Valproic acid prepared by cyanoacetic acid ester method 湖南省湘中制药有限公司 2024-07-23 CN claimed
CN-116143658-A Method for simultaneously preparing tripropylacetonitrile, tripropylamide and tripropylacetic acid 上海青平药业有限公司 2023-05-23 CN claimed
CN-113200844-A Preparation method of sodium valproate 上海青平药业有限公司 2021-08-03 CN claimed
CN-113200848-A Novel preparation method of valproic acid 上海青平药业有限公司 2021-08-03 CN claimed
JP-56010135-A None JP disclosed
CN-120040282-A Method for removing impurity valeric acid of valproic acid in sodium valproate synthesis process 山东新华制药股份有限公司 2025-05-27 CN disclosed
CN-119930467-A Preparation method of 2-cyano-2-propyl valerate and valproic acid 湖南省湘中制药有限公司 2025-05-06 CN disclosed
CN-116082142-B Preparation method of sodium valproate 北京悦康科创医药科技股份有限公司 2025-03-04 CN disclosed
CN-118373735-B Valproic acid prepared by cyanoacetic acid ester method 湖南省湘中制药有限公司 2025-02-21 CN disclosed
CN-118373735-B Valproic acid prepared by cyanoacetic acid ester method 湖南省湘中制药有限公司 2025-02-21 CN disclosed
CN-118388335-A Method for controlling impurities in valproic acid 湖南省湘中制药有限公司 2024-07-26 CN disclosed
CN-113173845-A Method for preparing valproic acid 上海青平药业有限公司 2021-07-27 CN disclosed
WO-2008062471-A2 A MILD METHOD FOR THE PRODUCTION OF DI-N-PROPYLACETIC ACID (VALPROIC ACID) CALYX CHEMICALS AND PHARMACEUTICALS LTD. (IN) 2008-05-29 WO disclosed
EP-0087712-B1 METHOD FOR THE PREPARATION OF 3-CYANO-2-ALKYL ALKANALS AND USE OF 3-CYANO-2-ETHYL HEXANAL IN THE PREPARATION OF 2-PROPYLPENTANOIC ACID BASF Aktiengesellschaft (DE) 1986-05-07 EP disclosed
EP-0087712-A1 Method for the preparation of 3-cyano-2-alkyl alkanals and use of 3-cyano-2-ethyl hexanal in the preparation of 2-propylpentanoic acid BASF Aktiengesellschaft (DE) 1983-09-07 EP disclosed
US-4317925-A Process for the production of di-n-propylacetic acid RUHRCHEMIE AKTIENGESELLSCHAFT (DE) 1982-03-02 US disclosed
US-4311854-A DECARBONYLATION, HYDROGENATION RUHRCHEMIE AKTIENGESELLSCHAFT (DE) 1982-01-19 US disclosed
JP-S5610135-A PREPARATION OF DI-N-PROPYLMALONIC ACID KANEBO LTD 1981-02-02 JP disclosed