Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 2/20 | 0.47 |
| ▸ | PTGIR | P43119 | 2/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PTGFR | P43088 | 2/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | SLCO2A1 | Q92959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4734798 | 1.00 | PTGER2 (0.47) | PTGER2PTGIRPTGER1PTGER3PTGER4 | |
| SCHEMBL4734797 | 1.00 | PTGER2 (0.47) | PTGER2PTGIRPTGER1PTGER3PTGER4 | |
| SCHEMBL2053225 | 0.93 | PDE4D (0.42) | PTGER2PTGIRPTGER1PTGER3PTGER4 | |
| SCHEMBL2053223 | 0.93 | PDE4D (0.42) | PTGER2PTGIRPTGER1PTGER3PTGER4 | |
| SCHEMBL2053227 | 0.93 | PDE4D (0.42) | PTGER2PTGIRPTGER1PTGER3PTGER4 | |
| SCHEMBL1111542 | 0.93 | PDE4D (0.42) | PTGER2PTGIRPTGER1PTGER3PTGER4 | |
| SCHEMBL8092628 | 0.90 | PTGER2 (0.48) | PTGER2PTGIRPTGER1PTGER3PTGER4 | |
| SCHEMBL8079368 | 0.89 | PTGER2 (0.54) | PTGER2PTGIRPTGER1PTGER3PTGER4 | |
| SCHEMBL7583983 | 0.89 | PTGER2 (0.54) | PTGER2PTGIRPTGER1PTGER3PTGER4 | |
| SCHEMBL7592328 | 0.88 | PTGER2 (0.42) | PTGER2PTGIRPTGER1PTGER3PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073752-A2 | CYCLOBUTYL DERIVATIVES FOR THE TREATMENT OF GLAUCOMA | ALLERGAN, INC. (US) | 2008-06-19 | — | — | WO | disclosed |