Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 4/20 | 0.42 |
| ▸ | PTGIR | P43119 | 2/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7592396 | 0.95 | PTGER2 (0.39) | PTGER2PTGIRTBXA2RPTGER3PTGER1 | |
| SCHEMBL4734798 | 0.88 | PTGER2 (0.47) | PTGER2PTGIRTBXA2RPTGER3PTGER1 | |
| SCHEMBL4734793 | 0.88 | PTGER2 (0.47) | PTGER2PTGIRTBXA2RPTGER3PTGER1 | |
| SCHEMBL4734797 | 0.88 | PTGER2 (0.47) | PTGER2PTGIRTBXA2RPTGER3PTGER1 | |
| SCHEMBL8092628 | 0.84 | PTGER2 (0.48) | PTGER2PTGIRPTGER3PTGER1PTGER4 | |
| SCHEMBL7583983 | 0.83 | PTGER2 (0.54) | PTGER2PTGIRTBXA2RPTGER3PTGER1 | |
| SCHEMBL8079368 | 0.83 | PTGER2 (0.54) | PTGER2PTGIRTBXA2RPTGER3PTGER1 | |
| SCHEMBL7600274 | 0.83 | PTGER2 (0.59) | PTGER2PTGIRTBXA2RPTGER3PTGER1 | |
| SCHEMBL8087920 | 0.83 | PTGER2 (0.59) | PTGER2PTGIRTBXA2RPTGER3PTGER1 | |
| SCHEMBL2053223 | 0.82 | PDE4D (0.42) | PTGER2PTGIRPTGER3PTGER1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0860430-B1 | Omega-cycloalkyl-prostaglandin E2 derivatives | ONO PHARMACEUTICAL CO (JP) | 2002-06-12 | — | — | EP | disclosed |
| US-6110969-A | Cycloalkyl-prostaglandin E2 derivatives | ONO PHARMACEUTICAL CO. LTD. (JP) | 2000-08-29 | — | — | US | disclosed |
| EP-0860430-A2 | Omega-cycloalkyl-prostaglandin E2 derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-08-26 | — | — | EP | disclosed |