SCHEMBL8092628

CCC1(C(C/C=C/[C@@H]2[C@@H](C/C=C\CCCC(=O)O)[C@@H](OC(C)=O)C[C@H]2O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)CCC1

nearest known ligand 0.48

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	PTGER2	P43116	2/20	0.48

▸	PTGIR	P43119	2/20	0.48

▸	PDE4D	Q08499	8/20	0.45

▸	PTGER1	P34995	1/20	0.40

▸	PTGER4	P35408	1/20	0.40

▸	PTGER3	P43115	1/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7584569	0.94	PTGER2 (0.43)	PTGER2PTGIRPDE4DPTGER1PTGER4
SCHEMBL8079368	0.90	PTGER2 (0.54)	PTGER2PTGIRPDE4DPTGER1PTGER4
SCHEMBL7583983	0.90	PTGER2 (0.54)	PTGER2PTGIRPDE4DPTGER1PTGER4
SCHEMBL4734797	0.90	PTGER2 (0.47)	PTGER2PTGIRPDE4DPTGER1PTGER4
SCHEMBL4734798	0.90	PTGER2 (0.47)	PTGER2PTGIRPDE4DPTGER1PTGER4
SCHEMBL4734793	0.90	PTGER2 (0.47)	PTGER2PTGIRPDE4DPTGER1PTGER4
SCHEMBL7600274	0.89	PTGER2 (0.59)	PTGER2PTGIRPDE4DPTGER1PTGER4
SCHEMBL8087920	0.89	PTGER2 (0.59)	PTGER2PTGIRPDE4DPTGER1PTGER4
SCHEMBL7591974	0.85	PTGER2 (0.43)	PTGER2PTGIRPTGER1PTGER4PTGER3
SCHEMBL7592328	0.84	PTGER2 (0.42)	PTGER2PTGIRPDE4DPTGER1PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-6110969-A	Cycloalkyl-prostaglandin E2 derivatives	ONO PHARMACEUTICAL CO. LTD. (JP)	2000-08-29	—	—	US	disclosed
EP-0860430-A2	Omega-cycloalkyl-prostaglandin E2 derivatives	ONO PHARMACEUTICAL CO., LTD. (JP)	1998-08-26	—	—	EP	disclosed