Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 5/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4706604 | 0.85 | NPC1 (0.66) | POLBHPGDCYP1A2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL2990660 | 0.84 | NPC1 (0.64) | POLBHPGDCYP1A2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL4707532 | 0.84 | NPC1 (0.64) | POLBHPGDCYP1A2NPC1RAB9A | |
| SCHEMBL10605231 | 0.82 | POLB (0.64) | POLBHPGDCYP1A2NPC1RAB9A | |
| SCHEMBL406614 | 0.82 | POLB (0.69) | POLBHPGDCYP1A2NPC1RAB9A | |
| SCHEMBL4148749 | 0.81 | HPGD (0.70) | POLBHPGDCYP1A2NPC1RAB9A | |
| SCHEMBL11366306 | 0.81 | POLB (0.62) | POLBHPGDCYP1A2NPC1RAB9A | |
| SCHEMBL11146717 | 0.81 | HPGD (0.67) | POLBHPGDCYP1A2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL2452557 | 0.80 | POLB (0.67) | POLBHPGDCYP1A2NPC1RAB9A | |
| SCHEMBL9492505 | 0.79 | HPGD (0.78) | POLBHPGDCYP1A2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582696-B1 | 5-ARYL ISOXAZOLINES FOR CONTROLLING PESTS | NOVARTIS AG (CH) | 2014-10-22 | — | — | EP | disclosed |
| WO-2011157748-A1 | 5-ARYL ISOXAZOLINES FOR CONTROLLING PESTS | NOVARTIS AG (CH) | 2011-12-22 | — | — | WO | disclosed |