Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | CES2 | O00748 | 1/20 | 0.58 |
| ▸ | CES1 | P23141 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CTSD | P07339 | 1/20 | 0.53 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.53 |
| ▸ | FEN1 | P39748 | 1/20 | 0.53 |
| ▸ | SMO | Q99835 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2452557 | 0.98 | POLB (0.67) | POLBHPGDCYP1A2KDM4EALDH1A1 | |
| Acetonitrile SCHEMBL28068508 | 0.89 | POLB (0.56) | POLBHPGDCYP1A2KDM4EALDH1A1 | |
| SCHEMBL30547074 | 0.84 | CTSD (0.63) | KDM4EALDH1A1MAPTCA1CA2 | |
| SCHEMBL239328 | 0.84 | CTSD (0.63) | KDM4EALDH1A1MAPTCA1CA2 | |
| SCHEMBL27539648 | 0.83 | HPGD (0.61) | POLBHPGDCYP1A2KDM4EALDH1A1 | |
| SCHEMBL3607272 | 0.83 | KLKB1 (0.61) | POLBKDM4EALDH1A1MAPTCA1 | |
| SCHEMBL4384455 | 0.83 | TAS1R3 (0.60) | POLBKDM4EALDH1A1MAPTNPC1 | |
| SCHEMBL8373805 | 0.82 | POLB (1.00) | POLBHPGDCYP1A2KDM4EALDH1A1 | |
| SCHEMBL10558954 | 0.82 | ALDH1A1 (0.50) | POLBHPGDKDM4EALDH1A1MAPT | |
| SCHEMBL47348 | 0.82 | POLB (0.62) | POLBHPGDCYP1A2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 336 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117402125-A | Preparation method of noo Bo Suan oxadiazole thioester compound, product and application thereof | 南京林业大学 | 2024-01-16 | — | — | CN | claimed |
| US-11398630-B2 | Method of generating energy from a hydrazide containing anode fuel, and fuel cell | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2022-07-26 | — | — | US | claimed |
| US-20210005900-A1 | METHOD OF GENERATING ENERGY FROM A HYDRAZIDE CONTAINING ANODE FUEL, AND FUEL CELL | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2021-01-07 | — | — | US | claimed |
| CN-106397420-B | 3- (5- aryl-1,3,4-oxdiazole -2- bases) asarinin analog derivative, preparation method and application | 郑州大学 | 2018-10-09 | — | — | CN | claimed |
| US-10040741-B2 | Method for manufacturing high purity glycol based compound | SAMSUNG DISPLAY CO., LTD. (KR) | 2018-08-07 | — | — | US | claimed |
| CN-107973807-A | Triazolobenzothiazole derivative and preparation method and application thereof | 唐山学院 | 2018-05-01 | — | — | CN | claimed |
| CN-106380475-B | A kind of thieno [2,3 d] pyrimidines and its preparation method and application | 湖北民族学院 | 2018-03-09 | — | — | CN | claimed |
| CN-107188827-A | The preparation method of o-chlorobenzoyl hydrazine | 重庆锦杉科技有限公司 | 2017-09-22 | — | — | CN | claimed |
| CN-106928088-A | A kind of synthetic method of o-chlorobenzoyl hydrazine | 李亚杉 | 2017-07-07 | — | — | CN | claimed |
| CN-106397420-A | 3-(5-aryl-1,3-4-oxadiazole-2-yl)sarisan derivatives, and preparation method and application thereof | 郑州大学 | 2017-02-15 | — | — | CN | claimed |
| US-20080245233-A1 | Method for Inhibiting Fouling in Basic Washing Systems | BAKER HUGHES INCORPORATED (US) | 2008-10-09 | — | — | US | claimed |
| EP-1602678-B1 | Cure accelerators | HEXCEL COMPOSITES LTD (GB) | 2008-06-11 | — | — | EP | claimed |
| US-20050272883-A1 | Cure accelerators | HEXCEL COMPOSITES, LTD. (GB) | 2005-12-08 | — | — | US | claimed |
| US-20050239853-A1 | New compounds | BIOVITRUM AB (SE) | 2005-10-27 | — | — | US | claimed |
| WO-2005075471-A2 | THIAZOL-COMPOUNDS AS 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS | BIOVITRUM AB (SE) | 2005-08-18 | — | — | WO | claimed |
| US-20030105140-A1 | Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. | 2003-06-05 | — | — | US | claimed |
| WO-2002102301-A2 | SUBSTITUTED INDOLE-2-CARBOXYLIC ACID BENZYLIDENE-HYDRAZIDES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | CYTOVIA, INC. (US) | 2002-12-27 | — | — | WO | claimed |
| US-20020128292-A1 | Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. | 2002-09-12 | — | — | US | claimed |
| EP-0140886-B1 | FILM BADGE FOR DETERMINING CARBONYL COMPOUNDS | Crystal Diagnostic Systems, Inc. (US) | 1988-09-07 | — | — | EP | claimed |
| US-4229463-A | ANTICHOLESTEROL AGENTS FOR REDUCING CHOLESTEROL ESTER CONTENT OF ARTERIAL WALLS | SANDOZ, INC. (US) | 1980-10-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128292-A1 | Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof | BAD, API5, CASP2 | POLB 4305/4885HPGD 516/4885CYP1A2 502/4885 |
| US-20030105140-A1 | Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof | BAD, API5, CASP2 | POLB 4305/4885HPGD 516/4885CYP1A2 502/4885 |
| US-20050239853-A1 | New compounds | HSD11B1, CYP11B1, HSD3B1 | POLB 1038/4885HPGD 66/4885CYP1A2 48/4885 |
| US-10040741-B2 | Method for manufacturing high purity glycol based compound | GK, GMDS, UGCG | POLB 2497/4885HPGD 172/4885CYP1A2 1025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.