Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | ME2 | P23368 | 1/20 | 0.38 |
| ▸ | ME1 | P48163 | 1/20 | 0.38 |
| ▸ | ME3 | Q16798 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4734783 | 0.95 | OPRM1 (0.40) | KDM4EALDH1A1TSHRKMT2ARAB9A | |
| SCHEMBL4734158 | 0.91 | DRD4 (0.43) | KDM4EALDH1A1TSHRKMT2ARAB9A | |
| SCHEMBL4736796 | 0.91 | OPRM1 (0.49) | KDM4EALDH1A1TSHRMAPTOPRM1 | |
| SCHEMBL4786222 | 0.89 | KDM4E (0.49) | KDM4EALDH1A1TSHRKMT2ACETP | |
| SCHEMBL4739217 | 0.89 | MEN1 (0.42) | KDM4EALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL4738789 | 0.89 | OPRM1 (0.49) | KDM4EALDH1A1TSHROPRM1OPRK1 | |
| SCHEMBL4737955 | 0.89 | OPRM1 (0.43) | KDM4EALDH1A1TSHRKMT2ARAB9A | |
| SCHEMBL4738909 | 0.85 | TSHR (0.44) | KDM4EALDH1A1TSHRKMT2ARAB9A | |
| SCHEMBL4738192 | 0.84 | HRH3 (0.42) | TSHRKMT2AMEN1OPRM1OPRK1 | |
| SCHEMBL3830332 | 0.83 | MEN1 (0.45) | KDM4EALDH1A1TSHRKMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |