Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | ME2 | P23368 | 2/20 | 0.40 |
| ▸ | ME1 | P48163 | 2/20 | 0.40 |
| ▸ | ME3 | Q16798 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4734903 | 0.95 | KDM4E (0.41) | OPRM1OPRK1ME2ME1ME3 | |
| SCHEMBL4737955 | 0.91 | OPRM1 (0.43) | OPRM1OPRK1ME2ME1ME3 | |
| SCHEMBL4786222 | 0.90 | KDM4E (0.49) | OPRM1OPRK1ME2ME1ME3 | |
| SCHEMBL4734158 | 0.90 | DRD4 (0.43) | POLBSMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL4736796 | 0.88 | OPRM1 (0.49) | OPRM1OPRK1MAPTKDM4EALDH1A1 | |
| SCHEMBL4738192 | 0.87 | HRH3 (0.42) | OPRM1OPRK1ME2ME1ME3 | |
| SCHEMBL4738789 | 0.86 | OPRM1 (0.49) | OPRM1OPRK1ME2ME1ME3 | |
| SCHEMBL4739217 | 0.86 | MEN1 (0.42) | OPRM1OPRK1ME2ME1ME3 | |
| SCHEMBL4733765 | 0.84 | CNR2 (0.36) | OPRM1OPRK1KDM4EALDH1A1TSHR | |
| SCHEMBL4735433 | 0.84 | OPRM1 (0.40) | OPRM1OPRK1KDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |