Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 3/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4738300 | 0.92 | PTGER1 (0.58) | PTGER1BRD4HCAR2RXFP1NR1H2 | |
| SCHEMBL4734971 | 0.82 | PTGER1 (0.43) | PTGER1CES1RXFP1NR1H2NR1H3 | |
| SCHEMBL17610980 | 0.78 | PTGER1 (0.51) | PTGER1BRD4RXFP1PTGS1PTGS2 | |
| Trifluoroacetic Acid SCHEMBL4737901 | 0.73 | BRD4 (0.51) | BRD4TSHR | |
| SCHEMBL16519369 | 0.71 | PTGER1 (0.42) | PTGER1BRD4HCAR2RXFP1TSHR | |
| SCHEMBL23081441 | 0.70 | RIPK1 (0.51) | PTGER1BRD4 | |
| SCHEMBL30525763 | 0.70 | RIPK1 (0.51) | PTGER1BRD4 | |
| SCHEMBL16057682 | 0.70 | PTGER1 (0.43) | PTGER1BRD4RXFP1TSHRHIF1A | |
| SCHEMBL10883057 | 0.70 | PTGER1 (0.41) | PTGER1BRD4HCAR2RXFP1TSHR | |
| SCHEMBL28062278 | 0.70 | RXFP1 (0.42) | BRD4RXFP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |