Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 4/20 | 0.35 |
| ▸ | FAAH | O00519 | 3/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4734974 | 0.82 | PTGER1 (0.52) | PTGER1CES1RXFP1NR1H2NR1H3 | |
| SCHEMBL4738300 | 0.79 | PTGER1 (0.58) | PTGER1PKMRXFP1NR1H2NR1H3 | |
| SCHEMBL4737896 | 0.77 | BRD4 (0.41) | GABRA2GABRB2 | |
| SCHEMBL4737902 | 0.70 | RBP4 (0.46) | PKMTSHR | |
| SCHEMBL23081441 | 0.67 | RIPK1 (0.51) | PTGER1 | |
| SCHEMBL30525763 | 0.67 | RIPK1 (0.51) | PTGER1 | |
| SCHEMBL30881067 | 0.67 | GABRA2 (0.52) | GABRA2GABRB2RXFP1 | |
| SCHEMBL17610978 | 0.67 | GABRA2 (0.46) | GABRA2GABRB2 | |
| SCHEMBL28062278 | 0.66 | RXFP1 (0.42) | RXFP1TSHR | |
| SCHEMBL17610980 | 0.66 | PTGER1 (0.51) | PTGER1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |