SCHEMBL4735008

SCHEMBL4735008

COc1ccc(-c2c(C(=O)O)cc(O)c(O)c2O)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.54
GPR35 Q9HC97 3/20 0.50
ALDH1A1 P00352 3/20 0.46
KDM4E B2RXH2 2/20 0.46
HPGD P15428 2/20 0.46
GAA P10253 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
POLB P06746 1/20 0.46
PRKAB2 O43741 1/20 0.45
PRKAG1 P54619 1/20 0.45
PRKAA2 P54646 1/20 0.45
PRKAA1 Q13131 1/20 0.45
PRKAG3 Q9UGI9 1/20 0.45
PRKAG2 Q9UGJ0 1/20 0.45
PRKAB1 Q9Y478 1/20 0.45
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
XDH P47989 1/20 0.44
SLC22A12 Q96S37 1/20 0.44
NR4A2 P43354 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11021639 0.81 PRKAB2 (0.52) ALDH1A1GAAPRKAB2PRKAG1PRKAA2
SCHEMBL6383991 0.81 SMN1; SMN2 (0.54) SMN1; SMN2GPR35ALDH1A1KDM4EHPGD
SCHEMBL6846496 0.80 ACMSD (0.52) SMN1; SMN2GPR35ALDH1A1KDM4EHPGD
SCHEMBL31237054 0.79 ACMSD (0.50) GPR35ALDH1A1KDM4EHPGDCA1
SCHEMBL10873531 0.76 SMN1; SMN2 (0.51) SMN1; SMN2GPR35ALDH1A1KDM4EHPGD
SCHEMBL27592786 0.76 AKR1C2 (0.39) GPR35AKR1C3AKR1C2RECQL
SCHEMBL8353016 0.76 SMN1; SMN2 (0.59) SMN1; SMN2GPR35ALDH1A1KDM4EHPGD
SCHEMBL5885105 0.76 MCL1 (0.67) SMN1; SMN2RECQL
SCHEMBL674849 0.75 SELL (0.50) SMN1; SMN2ALDH1A1KDM4EHPGDCA1
SCHEMBL31674337 0.75 SELL (0.50) SMN1; SMN2ALDH1A1KDM4EHPGDCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008065527-A2 GALLIC ACID ESTERS OF FRAGRANT ALCOHOLS GHISALBERTI CARLO (BR) 2008-06-05 WO disclosed