Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4734189 | 0.84 | KMT2A (0.46) | ADORA1KMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL4735595 | 0.73 | KDR (0.38) | ADORA1KMT2AMEN1POLBMAPT | |
| SCHEMBL3801893 | 0.72 | ADORA1 (0.44) | ADORA1KMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL26038538 | 0.70 | ALDH1A1 (0.40) | KMT2AMEN1POLBL3MBTL1MAPT | |
| SCHEMBL18701492 | 0.70 | ADORA2A (0.36) | ADORA1KMT2AL3MBTL1MAPTHSD17B10 | |
| SCHEMBL16316421 | 0.70 | ADORA1 (0.56) | ADORA1KMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL14208608 | 0.70 | ADORA1 (0.38) | ADORA1KMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL26042354 | 0.68 | DHODH (0.44) | ADORA1KMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL9213881 | 0.68 | ADORA1 (0.40) | ADORA1KMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL5313613 | 0.68 | MAPK1 (0.51) | ADORA1KMT2AL3MBTL1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008059368-A2 | FUSED 2-AMINO PYRIMIDINE COMPOUNDS AND THEIR USE FOR THE TREATMENT OF CANCER | PFIZER PRODUCTS INC. (US) | 2008-05-22 | — | — | WO | disclosed |