Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 12/20 | 0.55 |
| ▸ | ITGA4 | P13612 | 10/20 | 0.55 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGAV | P06756 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733969 | 0.94 | ITGA4 (0.54) | ITGB1ITGA4MEN1KMT2APDE4B | |
| SCHEMBL4730854 | 0.91 | ITGB1 (0.64) | ITGB1ITGA4ITGB7ITGA5ITGB3 | |
| SCHEMBL4730816 | 0.91 | ITGB1 (0.64) | ITGB1ITGA4ITGB7ITGA5ITGB3 | |
| SCHEMBL4732547 | 0.85 | ITGA4 (0.62) | ITGB1ITGA4ITGB7ITGA5ITGB3 | |
| SCHEMBL4736103 | 0.85 | ITGA4 (0.62) | ITGB1ITGA4ITGB7ITGA5ITGB3 | |
| SCHEMBL4736084 | 0.85 | ITGA4 (0.62) | ITGB1ITGA4ITGB7ITGA5ITGB3 | |
| SCHEMBL4735453 | 0.82 | ITGA4 (0.40) | ITGB1ITGA4ITGB7ITGA5 | |
| SCHEMBL4734792 | 0.82 | ITGA4 (0.40) | ITGB1ITGA4ITGB7ITGA5 | |
| SCHEMBL4733515 | 0.81 | ITGB1 (0.59) | ITGB1ITGA4 | |
| SCHEMBL4736260 | 0.81 | ITGB1 (0.59) | ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008064823-A1 | BICYCLIC AND HETEROBICYCLIC DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB PHARMA, S.A. (BE) | 2008-06-05 | — | — | WO | claimed |
| WO-2008064823-A1 | BICYCLIC AND HETEROBICYCLIC DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB PHARMA, S.A. (BE) | 2008-06-05 | — | — | WO | disclosed |