Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 15/20 | 0.54 |
| ▸ | ITGB1 | P05556 | 14/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4735182 | 0.94 | ITGB1 (0.55) | ITGA4ITGB1PDE4BPDE4DMEN1 | |
| SCHEMBL4732547 | 0.91 | ITGA4 (0.62) | ITGA4ITGB1CYP3A4 | |
| SCHEMBL4736103 | 0.91 | ITGA4 (0.62) | ITGA4ITGB1CYP3A4 | |
| SCHEMBL4736084 | 0.91 | ITGA4 (0.62) | ITGA4ITGB1CYP3A4 | |
| SCHEMBL4730854 | 0.85 | ITGB1 (0.64) | ITGA4ITGB1 | |
| SCHEMBL4730816 | 0.85 | ITGB1 (0.64) | ITGA4ITGB1 | |
| SCHEMBL4731194 | 0.83 | ITGA4 (0.42) | ITGA4ITGB1 | |
| SCHEMBL4734887 | 0.83 | ITGA4 (0.42) | ITGA4ITGB1 | |
| SCHEMBL4786565 | 0.81 | ITGA4 (0.58) | ITGA4ITGB1CYP3A4PDE4B | |
| SCHEMBL4733515 | 0.80 | ITGB1 (0.59) | ITGA4ITGB1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008064823-A1 | BICYCLIC AND HETEROBICYCLIC DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB PHARMA, S.A. (BE) | 2008-06-05 | — | — | WO | claimed |
| WO-2008064823-A1 | BICYCLIC AND HETEROBICYCLIC DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB PHARMA, S.A. (BE) | 2008-06-05 | — | — | WO | disclosed |