Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | TYR | P14679 | 5/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5015560 | 0.82 | PRKCI (0.54) | GABRA1GABRB2CYP3A4ALOX15TDP1 | |
| SCHEMBL11673857 | 0.78 | HTR2A (0.42) | GABRA1GABRB2EGFRTYRTDP1 | |
| SCHEMBL5877825 | 0.76 | GABRA1 (0.68) | GABRA1GABRB2EGFRTYRCYP3A4 | |
| SCHEMBL14283781 | 0.75 | GABRA1 (0.43) | GABRA1GABRB2EGFRTYRCYP3A4 | |
| SCHEMBL111318 | 0.74 | EGFR (0.47) | GABRA1GABRB2EGFRTYRCYP3A4 | |
| SCHEMBL19902003 | 0.74 | TYR (0.40) | GABRA1GABRB2EGFRTYRCYP3A4 | |
| SCHEMBL29408416 | 0.73 | ESR1 (0.57) | EGFRTYRCYP3A4ALOX15TP53 | |
| SCHEMBL71448 | 0.73 | ESR1 (0.57) | EGFRTYRCYP3A4ALOX15TP53 | |
| SCHEMBL632575 | 0.73 | HTR1A (0.54) | GABRA1GABRB2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9169831 | 0.73 | GABRA1 (0.48) | GABRA1GABRB2EGFRTYRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008066758-A1 | METHODS FOR PURIFYING SILOXANYL MONOMERS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2008-06-05 | — | — | WO | disclosed |