Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 3/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.34 |
| ▸ | GPR183 | P32249 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.31 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3808537 | 0.94 | CACNA1G (0.34) | CACNA1GCACNA1HFKBP1ARXFP1 | |
| SCHEMBL3671643 | 0.91 | CHRM5 (0.39) | KDM4ELMNAGAA | |
| SCHEMBL3665443 | 0.91 | RXFP1 (0.36) | CACNA1GCACNA1HL3MBTL1FKBP1ARXFP1 | |
| SCHEMBL4800257 | 0.87 | OPRL1 (0.36) | CACNA1GCACNA1HOPRM1 | |
| SCHEMBL3665336 | 0.86 | CHRM5 (0.36) | CACNA1GCACNA1H | |
| SCHEMBL3667342 | 0.86 | CHRM1 (0.34) | CACNA1GCACNA1HOPRM1RXFP1KDM4E | |
| SCHEMBL4737981 | 0.84 | CACNA1G (0.33) | CACNA1GCACNA1H | |
| SCHEMBL3665332 | 0.81 | POLB (0.35) | CACNA1GCACNA1HOPRM1AGTR2 | |
| SCHEMBL3669383 | 0.80 | CYP3A4 (0.37) | CACNA1GCACNA1HLMNAGAA | |
| SCHEMBL3806319 | 0.79 | CHRM5 (0.36) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1997805-A1 | Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans | Commissariat à l'Energie Atomique (FR) | 2008-12-03 | — | — | EP | claimed |