Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 6/20 | 0.34 |
| ▸ | DRD2 | P14416 | 4/20 | 0.34 |
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | DRD3 | P35462 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | MLNR | O43193 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.34 |
| ▸ | DRD1 | P21728 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3665443 | 0.94 | RXFP1 (0.36) | RXFP1KDM4ECACNA1GCACNA1HALDH1A1 | |
| SCHEMBL3808537 | 0.90 | CACNA1G (0.34) | CHRM1DRD2CYP2D6RXFP1CACNA1G | |
| SCHEMBL3665336 | 0.89 | CHRM5 (0.36) | CACNA1GCACNA1HTSHRAVPR1ANPSR1 | |
| SCHEMBL3668869 | 0.89 | BCHE (0.33) | OPRK1KDM4ECACNA1GCACNA1HALDH1A1 | |
| SCHEMBL3671643 | 0.86 | CHRM5 (0.39) | LMNACHRM2CYP2D6KDM4EALDH1A1 | |
| SCHEMBL4735430 | 0.86 | CACNA1G (0.35) | LMNARXFP1KDM4ECACNA1GCACNA1H | |
| SCHEMBL4800257 | 0.84 | OPRL1 (0.36) | HTR2ACYP2D6HTR2COPRK1CACNA1G | |
| SCHEMBL3665332 | 0.82 | POLB (0.35) | OPRK1CACNA1GCACNA1HALDH1A1AGTR1 | |
| SCHEMBL1838176 | 0.81 | OPRK1 (0.50) | CHRM1DRD2HTR1AHTR2ADRD3 | |
| SCHEMBL1836260 | 0.81 | OPRK1 (0.50) | CHRM1DRD2HTR1AHTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155676-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS | Commissariat à l'Energie Atomique (FR) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008146172-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2008-12-04 | — | — | WO | disclosed |