Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 8/20 | 0.61 |
| ▸ | BACE1 | P56817 | 3/20 | 0.54 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.54 |
| ▸ | CASP1 | P29466 | 2/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29408005 | 0.93 | OPRD1 (0.68) | OPRD1BACE1BACE2CASP1OPRM1 | |
| SCHEMBL4735755 | 0.92 | OPRD1 (0.65) | OPRD1BACE1BACE2CASP1OPRM1 | |
| SCHEMBL29409609 | 0.88 | OPRD1 (0.64) | OPRD1BACE1BACE2CASP1OPRM1 | |
| SCHEMBL30079821 | 0.87 | OPRD1 (0.58) | OPRD1BACE1BACE2OPRM1OPRK1 | |
| SCHEMBL31404908 | 0.85 | OPRD1 (0.66) | OPRD1BACE1BACE2CASP1OPRM1 | |
| SCHEMBL30973962 | 0.85 | OPRD1 (0.61) | OPRD1BACE1BACE2CASP1 | |
| SCHEMBL31257068 | 0.84 | OPRD1 (0.64) | OPRD1BACE1BACE2CASP1OPRM1 | |
| SCHEMBL29359045 | 0.84 | OPRD1 (0.61) | OPRD1BACE1BACE2CASP1OPRM1 | |
| SCHEMBL29946109 | 0.84 | CASP1 (0.61) | OPRD1BACE1BACE2CASP1OPRM1 | |
| SCHEMBL9241543 | 0.82 | CASP1 (0.67) | OPRD1BACE1BACE2CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008079408-A1 | A ZEBRAFISH BASED SCREEN FOR AGENTS WITH ABILITY TO PREVENT CELL DEATH | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2008-07-03 | — | — | WO | disclosed |