Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.71 |
| ▸ | MAPT | P10636 | 9/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.71 |
| ▸ | DHFR | P00374 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.66 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.63 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.63 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | HPGD | P15428 | 6/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.56 |
| ▸ | CASP1 | P29466 | 5/20 | 0.56 |
| ▸ | CASP7 | P55210 | 5/20 | 0.56 |
| ▸ | TP53 | P04637 | 5/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL155995 | 0.90 | MEN1 (0.71) | MEN1KMT2ACYP3A4HSD17B10KDM4E | |
| SCHEMBL5425962 | 0.89 | MEN1 (0.66) | MEN1KMT2ACYP3A4HSD17B10KDM4E | |
| SCHEMBL505584 | 0.84 | MEN1 (0.79) | MEN1KMT2ACYP3A4HSD17B10KDM4E | |
| SCHEMBL505415 | 0.84 | DHFR (0.68) | MEN1KMT2ACYP3A4HSD17B10KDM4E | |
| SCHEMBL2281134 | 0.83 | MEN1 (1.00) | MEN1KMT2ACYP3A4HSD17B10KDM4E | |
| SCHEMBL1627936 | 0.81 | CYP3A4 (0.82) | MEN1KMT2ACYP3A4HSD17B10KDM4E | |
| SCHEMBL15456750 | 0.81 | CYP3A4 (0.82) | MEN1KMT2ACYP3A4HSD17B10KDM4E | |
| SCHEMBL1628821 | 0.80 | DHFR (1.00) | MEN1KMT2ACYP3A4HSD17B10KDM4E | |
| SCHEMBL2987776 | 0.79 | ATP1A1 (0.61) | MEN1KMT2ACYP3A4HSD17B10KDM4E | |
| SCHEMBL24474227 | 0.78 | MEN1 (0.83) | MEN1KMT2ACYP3A4HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008086400-A2 | SIRTUIN-ACTIVATING COMPOUNDS OF ENHANCED BIOAVAILABILITY | ISP INVESTMENTS INC. (US) | 2008-07-17 | — | — | WO | claimed |
| WO-2008086400-A2 | SIRTUIN-ACTIVATING COMPOUNDS OF ENHANCED BIOAVAILABILITY | ISP INVESTMENTS INC. (US) | 2008-07-17 | — | — | WO | disclosed |