Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 2/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 5/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3071006 | 0.90 | CACNA1H (0.47) | CACNA1HAOC3LTB4R2CNR2BCL2A1 | |
| SCHEMBL3815393 | 0.87 | CACNA1H (0.45) | CACNA1HAOC3LTB4R2CNR2CNR1 | |
| SCHEMBL3064331 | 0.87 | CACNA1H (0.45) | CACNA1HAOC3LTB4R2CNR2BCL2A1 | |
| SCHEMBL3816063 | 0.86 | CACNA1H (0.45) | CACNA1HAOC3LTB4R2CNR2CNR1 | |
| SCHEMBL3825186 | 0.85 | CACNA1H (0.44) | CACNA1HAOC3LTB4R2CNR2CNR1 | |
| SCHEMBL3063271 | 0.85 | RIPK1 (0.49) | CACNA1HAOC3LTB4R2CNR2BCL2A1 | |
| Trifluoroacetic Acid SCHEMBL3054195 | 0.84 | CACNA1H (0.42) | CACNA1HAOC3LTB4R2CNR2CNR1 | |
| SCHEMBL3065942 | 0.84 | CACNA1H (0.46) | CACNA1HAOC3LTB4R2CNR2BCL2A1 | |
| SCHEMBL3821700 | 0.83 | CNR2 (0.49) | CACNA1HAOC3LTB4R2CNR2CNR1 | |
| SCHEMBL3824486 | 0.83 | CACNA1H (0.41) | CACNA1HAOC3LTB4R2CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |