Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3825186 | 0.86 | CACNA1H (0.44) | CACNA1HAOC3MAPK14LTB4R2CNR2 | |
| SCHEMBL4736030 | 0.83 | CACNA1H (0.47) | CACNA1HAOC3MAPK14LTB4R2CNR2 | |
| SCHEMBL3823354 | 0.82 | CACNA1H (0.40) | CACNA1HTDP1AOC3MAPK14LTB4R2 | |
| SCHEMBL3820052 | 0.82 | CACNA1H (0.40) | CACNA1HTDP1AOC3MAPK14LTB4R2 | |
| SCHEMBL3071006 | 0.81 | CACNA1H (0.47) | CACNA1HAOC3MAPK14LTB4R2CNR2 | |
| SCHEMBL3815393 | 0.80 | CACNA1H (0.45) | CACNA1HAOC3LTB4R2CNR2CNR1 | |
| SCHEMBL3064331 | 0.78 | CACNA1H (0.45) | CACNA1HAOC3LTB4R2CNR2GRIA2 | |
| SCHEMBL3816063 | 0.77 | CACNA1H (0.45) | CACNA1HTDP1AOC3LTB4R2CNR2 | |
| SCHEMBL3063271 | 0.76 | RIPK1 (0.49) | CACNA1HAOC3LTB4R2CNR2GRIA2 | |
| Trifluoroacetic Acid SCHEMBL3054195 | 0.76 | CACNA1H (0.42) | CACNA1HAOC3LTB4R2CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091917-A1 | ION CHANNEL MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2009-08-26 | — | — | EP | claimed |
| WO-2008073934-A1 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |