Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | QPCT | Q16769 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4738754 | 0.83 | KMT2A (0.39) | KDM4EL3MBTL1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL4740303 | 0.77 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2GAAKMT2AMAPT | |
| SCHEMBL17844294 | 0.74 | TAS2R38 (0.43) | L3MBTL1ALDH1A1SMN1; SMN2HPGDGAA | |
| SCHEMBL10662571 | 0.70 | KDM4E (0.67) | KDM4EL3MBTL1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL5227550 | 0.69 | — | — | |
| SCHEMBL2764566 | 0.68 | ATM (0.61) | KDM4EL3MBTL1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL9247348 | 0.68 | — | — | |
| SCHEMBL1886498 | 0.68 | HTT (0.53) | KDM4EL3MBTL1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL4737919 | 0.67 | SMN1; SMN2 (0.48) | KDM4EL3MBTL1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL14031287 | 0.66 | KDM4E (0.57) | KDM4EL3MBTL1ALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008077170-A2 | BENZOTHIOAMIDES, AND USE THEREOF FOR RELAXING SMOOTH MUSCLES | Universität Wien (AT) | 2008-07-03 | — | — | WO | disclosed |