Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.32 |
| ▸ | MMP9 | P14780 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5066407 | 0.86 | MMP2 (0.34) | MMP2MMP9HPGD | |
| SCHEMBL4734992 | 0.81 | MMP2 (0.31) | MMP2MMP9HPGD | |
| SCHEMBL4906420 | 0.78 | CNR1 (0.41) | HPGD | |
| SCHEMBL4735172 | 0.78 | DRD2 (0.32) | HPGDCHRM1 | |
| SCHEMBL5067184 | 0.74 | BACE1 (0.39) | — | |
| SCHEMBL5066397 | 0.74 | RXFP1 (0.35) | MMP2MMP9 | |
| SCHEMBL4733748 | 0.72 | — | — | |
| SCHEMBL4783633 | 0.71 | BACE1 (0.50) | — | |
| SCHEMBL4738183 | 0.71 | MMP2 (0.33) | MMP2MMP9 | |
| SCHEMBL5067168 | 0.70 | RXFP1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008076046-A1 | NOVEL 2-AMINO-5, 5-DIARYL-IMIDAZOL-4-ONES | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | disclosed |