Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740023 | 0.81 | ALDH1A1 (0.51) | KDM4ERAB9ANPC1HSD17B10MEN1 | |
| SCHEMBL8873477 | 0.81 | KDM4E (0.53) | KDM4ERAB9ANPC1HSD17B10MEN1 | |
| SCHEMBL28696302 | 0.75 | CCR1 (0.41) | KDM4ERAB9ANPC1GRIN2DGRIN3B | |
| SCHEMBL8872656 | 0.75 | KDM4E (0.53) | KDM4ERAB9ANPC1HSD17B10MEN1 | |
| SCHEMBL8872860 | 0.71 | GRIN2D (0.51) | KDM4ERAB9ANPC1KMT2AXDH | |
| SCHEMBL8872788 | 0.70 | KDM4E (0.53) | KDM4ERAB9ANPC1HSD17B10MEN1 | |
| SCHEMBL8874107 | 0.70 | RAB9A (0.53) | KDM4ERAB9ANPC1HSD17B10XDH | |
| SCHEMBL22251408 | 0.69 | ADORA2A (0.48) | KDM4EHSD17B10MEN1CASP1KMT2A | |
| SCHEMBL8873758 | 0.69 | KDM4E (0.64) | KDM4ERAB9ANPC1HSD17B10MEN1 | |
| SCHEMBL1352743 | 0.69 | KDM4E (0.55) | KDM4ERAB9ANPC1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008081266-A1 | COMPOUNDS FOR THE TREATMENT OR PREVENTION OF INFECTION BY FLAVIVIRIDAE | CARTA ANTONIO (IT) | 2008-07-10 | — | — | WO | claimed |
| WO-2008081266-A1 | COMPOUNDS FOR THE TREATMENT OR PREVENTION OF INFECTION BY FLAVIVIRIDAE | CARTA ANTONIO (IT) | 2008-07-10 | — | — | WO | disclosed |
| WO-2008081266-A1 | COMPOUNDS FOR THE TREATMENT OR PREVENTION OF INFECTION BY FLAVIVIRIDAE | CARTA ANTONIO (IT) | 2008-07-10 | — | — | WO | disclosed |