Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 18/20 | 0.74 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737584 | 0.94 | FASN (0.74) | FASN | |
| SCHEMBL4737156 | 0.93 | FASN (0.72) | FASN | |
| SCHEMBL4731407 | 0.92 | FASN (0.71) | FASN | |
| SCHEMBL4784807 | 0.91 | FASN (0.70) | FASN | |
| SCHEMBL4731958 | 0.91 | FASN (0.72) | FASN | |
| SCHEMBL4733288 | 0.90 | FASN (0.78) | FASN | |
| SCHEMBL4735658 | 0.90 | FASN (0.69) | FASN | |
| SCHEMBL16802696 | 0.90 | FASN (0.69) | FASN | |
| SCHEMBL4733280 | 0.90 | FASN (0.69) | FASN | |
| SCHEMBL4735622 | 0.89 | FASN (0.68) | FASNSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008059214-A1 | BISAMLDE DERIVATIVES AND USE THEREOF AS FATTY ACID SYNTHASE INHIBITORS | ASTRAZENECA AB (SE) | 2008-05-22 | — | — | WO | disclosed |