Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.48 |
| ▸ | PPARA | Q07869 | 8/20 | 0.48 |
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4738645 | 0.90 | PPARA (0.51) | PPARGPPARACYSLTR2CYSLTR1 | |
| SCHEMBL4738692 | 0.83 | PPARA (0.65) | PPARGPPARACYSLTR2CYSLTR1STAT3 | |
| SCHEMBL4740398 | 0.82 | HTT (0.40) | PPARGPPARASTAT3HTTSMN1; SMN2 | |
| SCHEMBL4782940 | 0.80 | PPARG (0.45) | PPARGPPARA | |
| SCHEMBL4857496 | 0.78 | PPARG (0.42) | PPARGPPARACYSLTR2CYSLTR1 | |
| SCHEMBL4786066 | 0.76 | PPARG (0.40) | PPARGPPARA | |
| SCHEMBL4738592 | 0.74 | PPARA (0.68) | PPARGPPARACYSLTR2CYSLTR1SMN1; SMN2 | |
| SCHEMBL4738651 | 0.73 | PPARA (0.68) | PPARGPPARACYSLTR2CYSLTR1 | |
| SCHEMBL4887675 | 0.73 | PPARG (0.38) | PPARGPPARA | |
| SCHEMBL4853717 | 0.71 | PPARA (0.37) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008081096-A2 | QUINOLINYL DERIVATIVES, METHOD FOR PREPARING SAME, PHARMACEUTIC COMPOSITIONS CONTAINING SAME, AND USE THEREOF AS HYPOGLYCEMIANT AND HYPOLIPEMIANT AGENTS | LES LABORATOIRES SERVIER (FR) | 2008-07-10 | — | — | WO | disclosed |