Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.40 |
| ▸ | PPARA | Q07869 | 6/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4857496 | 0.91 | PPARG (0.42) | PPARGPPARAHRH4BCHEPTGES | |
| SCHEMBL4887675 | 0.88 | PPARG (0.38) | PPARGPPARAHRH4BCHEPTGES | |
| SCHEMBL4738645 | 0.87 | PPARA (0.51) | PPARGPPARA | |
| SCHEMBL4782940 | 0.86 | PPARG (0.45) | PPARGPPARAKDM4EMEN1ALDH1A1 | |
| SCHEMBL4853717 | 0.80 | PPARA (0.37) | PPARGPPARABCHEALOX5 | |
| SCHEMBL4736258 | 0.76 | PPARG (0.48) | PPARGPPARA | |
| SCHEMBL4740398 | 0.76 | HTT (0.40) | PPARGPPARAHRH4KDM4EALDH1A1 | |
| SCHEMBL4739882 | 0.71 | PPARA (0.59) | PPARGPPARA | |
| SCHEMBL4736226 | 0.69 | PPARG (0.43) | PPARGPPARAALOX5KDM4EALDH1A1 | |
| SCHEMBL4738651 | 0.69 | PPARA (0.68) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008081096-A2 | QUINOLINYL DERIVATIVES, METHOD FOR PREPARING SAME, PHARMACEUTIC COMPOSITIONS CONTAINING SAME, AND USE THEREOF AS HYPOGLYCEMIANT AND HYPOLIPEMIANT AGENTS | LES LABORATOIRES SERVIER (FR) | 2008-07-10 | — | — | WO | disclosed |