Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 10/20 | 0.37 |
| ▸ | PPARG | P37231 | 9/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 4/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4736224 | 0.88 | PPARA (0.49) | PPARAPPARGALOX5PPARDTRPM8 | |
| SCHEMBL4857496 | 0.81 | PPARG (0.42) | PPARAPPARGALOX5PPARDBCHE | |
| SCHEMBL4738645 | 0.80 | PPARA (0.51) | PPARAPPARG | |
| SCHEMBL4786066 | 0.80 | PPARG (0.40) | PPARAPPARGALOX5BCHE | |
| SCHEMBL4782940 | 0.79 | PPARG (0.45) | PPARAPPARGPPARD | |
| SCHEMBL4887675 | 0.77 | PPARG (0.38) | PPARAPPARGALOX5PPARDBCHE | |
| SCHEMBL4736226 | 0.77 | PPARG (0.43) | PPARAPPARGALOX5TRPV1 | |
| SCHEMBL4740397 | 0.71 | PPARG (0.45) | PPARAPPARGALOX5PPARDTRPV1 | |
| SCHEMBL4740467 | 0.69 | PPARA (0.63) | PPARAPPARG | |
| SCHEMBL4739882 | 0.67 | PPARA (0.59) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008081096-A2 | QUINOLINYL DERIVATIVES, METHOD FOR PREPARING SAME, PHARMACEUTIC COMPOSITIONS CONTAINING SAME, AND USE THEREOF AS HYPOGLYCEMIANT AND HYPOLIPEMIANT AGENTS | LES LABORATOIRES SERVIER (FR) | 2008-07-10 | — | — | WO | disclosed |