Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIK2 | Q9H0K1 | 2/20 | 0.45 |
| ▸ | RIPK2 | O43353 | 3/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14161489 | 0.89 | RIPK2 (0.46) | SIK2RIPK2NOD2NPC1TLR9 | |
| SCHEMBL4737631 | 0.88 | SDHB (0.41) | SIK2NPC1TLR9LMNARAB9A | |
| SCHEMBL29536534 | 0.80 | SIK2 (0.47) | SIK2NPC1LMNAMAPTALDH1A1 | |
| SCHEMBL14370847 | 0.80 | SIK2 (0.47) | SIK2NPC1LMNAMAPTALDH1A1 | |
| SCHEMBL6341208 | 0.77 | MAPK14 (0.49) | SIK2RIPK2NOD2ACVR1MAPK14 | |
| SCHEMBL6336062 | 0.77 | MAPK14 (0.49) | SIK2RIPK2NOD2ACVR1MAPK14 | |
| SCHEMBL29545761 | 0.76 | FGFR1 (0.37) | NPC1TLR9RAB9AKMT2AMEN1 | |
| SCHEMBL20733929 | 0.76 | FGFR1 (0.37) | NPC1TLR9RAB9AKMT2AMEN1 | |
| SCHEMBL29535863 | 0.76 | RIPK2 (0.43) | SIK2RIPK2NPC1TLR9RAB9A | |
| SCHEMBL22719106 | 0.76 | RIPK2 (0.43) | SIK2RIPK2NPC1TLR9RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008078249-A1 | ANTI-INFLAMMATORY AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-07-03 | — | — | WO | disclosed |