Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1302395 | 0.83 | PTPN1 (0.44) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL4350121 | 0.81 | MEN1 (0.37) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL2493654 | 0.75 | CYP1A2 (0.36) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL1301737 | 0.75 | MAOA (0.43) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL13620937 | 0.74 | PDE4D (0.46) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL8173204 | 0.74 | MEN1 (0.55) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL4062559 | 0.71 | GABRP (0.36) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL8609293 | 0.71 | MAPT (0.51) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL4491054 | 0.71 | MAPT (0.38) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL4491052 | 0.71 | MAPT (0.38) | MAPTMEN1KMT2AALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008065522-A2 | PROCESS FOR THE SYNTHESIS OF 4-DIFLUOROMETHOXY-8-NITRO-1-FORMYL DIBENZO[B,D] FURAN-AN INTERMEDIATE FOR PDE IV INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-06-05 | — | — | WO | disclosed |