Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SFRP1 | Q8N474 | 14/20 | 0.67 |
| ▸ | WNT3 | P56703 | 6/20 | 0.59 |
| ▸ | CCR8 | P51685 | 1/20 | 0.58 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.57 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | STS | P08842 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4799560 | 0.87 | SFRP1 (0.62) | SFRP1WNT3CCR8NR1H2BRD4 | |
| SCHEMBL4736626 | 0.86 | SFRP1 (0.66) | SFRP1WNT3CCR8STS | |
| SCHEMBL4883255 | 0.86 | SFRP1 (0.59) | SFRP1WNT3CCR8NR1H2BRD4 | |
| SCHEMBL4725035 | 0.86 | SFRP1 (0.66) | SFRP1WNT3CCR8STS | |
| SCHEMBL4856222 | 0.85 | SFRP1 (0.61) | SFRP1WNT3CCR8NR1H2BRD4 | |
| SCHEMBL4617762 | 0.85 | SFRP1 (0.90) | SFRP1WNT3 | |
| SCHEMBL4734853 | 0.85 | SFRP1 (0.78) | SFRP1WNT3 | |
| SCHEMBL4735664 | 0.85 | SFRP1 (0.58) | SFRP1WNT3CCR8NR1H2BRD4 | |
| SCHEMBL4616091 | 0.85 | SFRP1 (0.75) | SFRP1WNT3 | |
| SCHEMBL4732035 | 0.85 | SFRP1 (0.60) | SFRP1WNT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061016-A1 | N-SUBSTITUTED PIPERIDINYL 4 -ARYLSULFONAMIDES AS MODULATORS OF THE SECRETED FRIZZLED RELATED PROTEIN- 1 | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |