Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 3/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24185773 | 0.84 | HPGD (0.53) | RAB9AHPGDSMN1; SMN2EPHX2L3MBTL1 | |
| SCHEMBL24185283 | 0.84 | HPGD (0.53) | RAB9AHPGDSMN1; SMN2EPHX2L3MBTL1 | |
| SCHEMBL4534421 | 0.84 | MAPT (0.67) | RAB9AHPGDSMN1; SMN2EPHX2L3MBTL1 | |
| SCHEMBL423224 | 0.83 | RAB9A (0.65) | RAB9AHPGDSMN1; SMN2L3MBTL1GRM5 | |
| SCHEMBL31392086 | 0.83 | RAB9A (0.65) | RAB9AHPGDSMN1; SMN2L3MBTL1L3MBTL3 | |
| SCHEMBL3242724 | 0.83 | RAB9A (0.65) | RAB9AHPGDSMN1; SMN2L3MBTL1L3MBTL3 | |
| SCHEMBL2431433 | 0.82 | GRM5 (0.53) | RAB9AHPGDSMN1; SMN2L3MBTL1L3MBTL3 | |
| SCHEMBL1980071 | 0.82 | L3MBTL3 (0.68) | RAB9AHPGDSMN1; SMN2EPHX2L3MBTL1 | |
| SCHEMBL13202942 | 0.82 | RAB9A (0.57) | RAB9AHPGDSMN1; SMN2EPHX2L3MBTL1 | |
| SCHEMBL8434306 | 0.82 | RAB9A (0.64) | RAB9AHPGDSMN1; SMN2EPHX2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061016-A1 | N-SUBSTITUTED PIPERIDINYL 4 -ARYLSULFONAMIDES AS MODULATORS OF THE SECRETED FRIZZLED RELATED PROTEIN- 1 | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |