Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.50 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.49 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737140 | 0.90 | MEN1 (0.64) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL4735039 | 0.87 | L3MBTL1 (0.56) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL4736437 | 0.82 | KMT2A (0.81) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL4737108 | 0.80 | POLB (0.59) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL4910018 | 0.79 | KMT2A (0.81) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL4734522 | 0.78 | ALDH1A1 (0.80) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL4734801 | 0.78 | KMT2A (0.57) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8483939 | 0.77 | KDM4E (0.72) | GRIK1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7464454 | 0.77 | L3MBTL1 (0.73) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL7463414 | 0.76 | L3MBTL1 (0.60) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008069611-A1 | N-PHENYLAMIDE DERIVATIVE, PROCESS FOR THE PREPARATION THEREOF, AND COMPOSITION FOR PREVENTING OR TREATING ISCHEMIC DISEASES COMPRISING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-06-12 | — | — | WO | claimed |
| WO-2008069611-A1 | N-PHENYLAMIDE DERIVATIVE, PROCESS FOR THE PREPARATION THEREOF, AND COMPOSITION FOR PREVENTING OR TREATING ISCHEMIC DISEASES COMPRISING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-06-12 | — | — | WO | disclosed |