Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 10/20 | 0.35 |
| ▸ | PPARA | Q07869 | 9/20 | 0.35 |
| ▸ | PPARG | P37231 | 8/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14146272 | 0.80 | CHRNA7 (0.40) | CTSSKAT6APTGS2 | |
| SCHEMBL4737604 | 0.78 | PPARD (0.45) | PPARDPPARAPPARGALDH1A1PTGDR2 | |
| SCHEMBL4736741 | 0.76 | MAOB (0.45) | CTSSPPARDPPARA | |
| SCHEMBL4736739 | 0.76 | MAOB (0.45) | CTSSPPARDPPARA | |
| SCHEMBL217859 | 0.75 | PPARA (0.39) | PPARDPPARAPPARG | |
| SCHEMBL219071 | 0.75 | HSD17B2 (0.41) | PPARDPPARAPPARGALDH1A1PTGDR2 | |
| SCHEMBL219874 | 0.75 | ERCC5 (0.41) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL217157 | 0.72 | ERCC5 (0.52) | PPARDPPARAPPARG | |
| SCHEMBL219974 | 0.72 | PPARD (0.43) | PPARDPPARAPPARGPTGDR2 | |
| SCHEMBL217887 | 0.71 | KDM4E (0.44) | PPARDPPARAPPARGKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | claimed |
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |