Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.38 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4736741 | 1.00 | MAOB (0.45) | MAOBLMNAMAPTGAAATM | |
| SCHEMBL4737615 | 0.80 | MAOB (0.44) | MAOBLMNAMAPTGAAATM | |
| SCHEMBL4737619 | 0.80 | MAOB (0.44) | MAOBLMNAMAPTGAAATM | |
| SCHEMBL4787159 | 0.78 | TNFRSF1A (0.55) | MAOBTNFRSF1A | |
| SCHEMBL4737608 | 0.78 | TNFRSF1A (0.55) | MAOBTNFRSF1A | |
| SCHEMBL4736804 | 0.77 | TNFRSF1A (0.46) | MAOBTNFRSF1A | |
| SCHEMBL4736808 | 0.77 | TNFRSF1A (0.46) | MAOBTNFRSF1A | |
| SCHEMBL4736815 | 0.76 | MRGPRX4 (0.35) | PPARAPPARDCTSS | |
| SCHEMBL4738535 | 0.75 | PPARG (0.44) | MAOBLMNAMAPTATMSMN1; SMN2 | |
| SCHEMBL4738538 | 0.75 | PPARG (0.44) | MAOBLMNAMAPTATMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | claimed |
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |